Igor Saveljic1, Dalibor Nikolic1, Zarko Milosevic1, Milica Nikolic, Antonis Sakellarios2, Themis P. Exarchos, Nenad Filipovic
19:30 - 20:30 | Tue 6 Mar | Caribbean ABC | TuPO.9
Atherosclerosis is a disease of arterial blood vessels characterized by the accumulation of lipids in the arterial wall. Mechanical forces such as low shear stress are implicated in plaque formation and development. Using DICOM images, 3D models of human right coronary artery (RCA) were developed. This paper studies influence of wall shear stress (WSS) on the atherosclerosis development. Three-dimensional blood flow was described with Navier-Stokes equation and continuity equation. Darcy`s Law was used to model mass transfer in the arterial wall. Kedem-Katchalsky equations were used for transports the low-density lipoproteins in the lumen and throw the vessel tissue. The results for plaque concentration for the RCA are presented.