High Speed X-Ray Analysis of Liquid Delivery during Jet Injection

Details

14:50 - 15:05 | Wed 12 Jul | Dunn Room | WeBT13.3

Session: Drug Delivery Routes, Release and Formulation

Abstract

The effect of varying velocity during jet injection on the dispersion of fluid into tissue is investigated using a custom-built X-ray imaging system. Injections are performed into ex-vivo porcine abdominal tissue using a voice coil actuated injection device. Single velocity and two-phase velocity injections reveal the complex nature of the dispersion of the fluid jet in layered tissue and highlight the effects of changing the jet velocity following the initial penetration of the liquid into the tissue.