Yuxuan Chen1, Jesse Farrand1, Julia Tang1, Yafen Chen1, Johnny O'Keeffe2, Guofa Shou1, Lei Ding, Han Yuan2
11:30 - 13:30 | Fri 26 May | Emerald III, Rose, Narcissus & Jasmine | FrPS1T1.65
Global signal regression (GSR) has been utilized as a pre-processing approach to eliminate the impact of global signal component across the brain in studies using resting-state functional magnetic resonance imaging (fMRI). But the procedure is under debate such that the underlying global signal could be of physiological origin. In this study, we aimed to address the controversy using functional near-infrared spectroscopy (fNIRS), which measures hemodynamic signals by probing local changes in oxygen consumption. Particularly, we acquired simultaneous EEG and fNIRS signals in healthy individuals at eyes open and eyes closed resting state and at different body positions. The present results revealed a negative relation between the changes across eyes-closed and eyes-open in fNIRS global signal amplitude and the changes in EEG vigilance.