Dynamic Brain Networks of Epileptic Patients with Generalized Tonic-Clonic Seizures

Luyan Zhang1, Yi Liang2, Fali Li1

  • 1University of Electronic Science and Technology of China
  • 2Sichuan Academy of Medical Sciences & Department Neurology

Details

11:30 - 13:30 | Fri 26 May | Emerald III, Rose, Narcissus & Jasmine | FrPS1T1.30

Session: Poster I

Abstract

Being the common type of epilepsy, the generalized tonic-clonic seizure is characterized by specific clinical symptoms, such as the loss of consciousness, physical convulsions, orthotonus and then clonicity. In the present study, the adaptive directed transfer function was applied to probe the dynamic brain network topological changes before, during and after the neurons' abnormal spiking. Findings showed that the brain network topological changes were closely related to the neurons' abnormal spiking, and also revealed the transferring of the brain activation to the epilepsy focus.