The Effect of Multiple Thin-Film Coatings of Protein Loaded Sol-Gel on Total Multi-Electrode Array Thickness

Matthew McDermott1, Kevin Otto2

  • 1Purdue University
  • 2Biomedical Engineering, University of Florida

Details

08:15 - 08:30 | Wed 17 Aug | Fantasia K | WeAT7.2

Session: Biomaterial-Cell Interactions

Abstract

Tetramethyl orthosilicate shows promise as a thin-film delivery vehicle for multi-electrode arrays for drug release and electrical performance; however, its effect upon device footprint has yet to be assessed. Using a previously established silicon wafer chip model, the thickness of one, two, and four protein doped coatings of sol-gel were analyzed via profilometry. Coating thickness was found to be 0.4µm, 1.1µm and 2.2µm on each side of the device. This addition to a native MEA is minimal when compared to other drug delivery paradigms currently associated with neural implants.