Regulation of Nuclear Morphology by Actomyosin Components and Cell Geometry

G.V. Shivashankar, Nisha M. Ramdas, Qingsen Li

Details

Category

Invited session papers

Theme

07. Cellular and Tissue Engineering and Biomaterials

Sessions

08:30 - 10:00 | Wed 26 Aug | White 2 | 7.1

Advanced technologies for Cell and Tissue Engineering

Abstract

Extracellular microenvironmental signals modulate the coupling between cytoskeleton to nuclear links to regulate gene expression profiles. However the influence of actomyosin assembly on the morphology of the nucleus is not well understood. In this paper, we quantitatively demonstrate the role of cell geometry and specific actomyosin molecular components in their control of nuclear morphology.

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